快餐一条龙400qq联系方式_100块钱附近人微信_附近一百元三个小时

中国医学科学院/北京协和医学院病原生物学研究所党委副书记、纪委书记、课题组组长。全国结核病防治综合质量控制专家指导委员会委员、中国免疫学会感染免疫分会委员、中国防痨协会结核病基础专业分会常委。《中华结核和呼吸杂志》和《结核与肺部疾病杂志》编委。
主要研究方向是感染、炎症与免疫机制研究。主持或参与国家科技重大专项、国家重点研发计划、国家自然科学基金、医学与健康科技创新工程等多项国家级和院校级科研项目，参与多项战略咨询项目研究。在SCI收录杂志上发表学术论文30余篇；获得6项发明专利授权；获得中华医学科学技术奖二等奖（排名第五）、重大专项创新团队奖。

结核病等我国重大传染病免疫机制及新型生物标识的研究。

1.    国家重点研发计划（2021-2026），结核病新型诊断、治疗、干预手段及产品研发，课题骨干。
2.    中国医学科学院中央级公益性科研院所基本科研业务费（2020-2022），西藏自治区结核病流行菌株特征及致病特点研究，课题负责人。
3.    国家自然科学基金委员会面上项目（2021-2024），血管生成素2参与活动性肺结核免疫机制研究，课题负责人。
4.    中国工程院咨询研究项目(2019-2020 )，中国与法国等发达国家结核病防治体系的对比研究，课题骨干。
5.    国家外专局高端外国专家项目(2018-1019)，结核病新型分子标识研究，课题负责人。
6.    国家科技重大专项 (2017-2020)，菌阴结核病和结核分枝杆菌潜伏感染相关生物标志物研究，子课题负责人。
7.    中国医学科学院医学与健康科技创新工程项目(2016-2021)，感染性疾病（结核病等）诊治新策略研究，课题骨干。
8.    国家自然科学基金委员会面上项目(2012-2015)，接头蛋白Gab2调控结核病发生、发展的免疫学功能研究，课题负责人。
9.    国家科技重大专项 (2012-2015)，结核病分子标识的研究，课题负责人。
10.    国家科技重大专项(2008-2010)，结核病免疫保护机制研究，课题负责人。
11.    国家科技重大专项 (2008-2010)，结核病诊断分子标识研究，子课题负责人。

1.    Dong, H., Y. Zhang, Y. Zou, Y. Chen, J. Yue, H. Liu and X. Jiang (2021). "Elevated chemokines concentration is associated with disease activity in Takayasu arteritis." Cytokine 143: 155515.
2.    Li, H., L. Liu, W. J. Zhang, X. Zhang, J. Zheng, L. Li, X. Zhu, Q. Yang, M. Zhang, H. Liu, X. Chen and Q. Jin (2019). "Analysis of the Antigenic Properties of Membrane Proteins of Mycobacterium tuberculosis." Sci Rep 9(1): 3042.
3.    Liu, C. H., H. Liu and B. Ge (2017). "Innate immunity in tuberculosis: host defense vs pathogen evasion." Cell Mol Immunol 14(12): 963-975.
4.    Hu, Y., Y. Zhang, X. Ren, Y. Liu, Y. Xiao, L. Li, F. Yang, H. Su, F. Liu, H. Liu, B. Cao and Q. Jin (2016). "A case report demonstrating the utility of next generation sequencing in analyzing serial samples from the lung following an infection with influenza A (H7N9) virus." J Clin Virol 76: 45-50.
5.    Yu, Y., D. Jin, S. Hu, Y. Zhang, X. Zheng, J. Zheng, M. Liao, X. Chen, M. Graner, H. Liu and Q. Jin (2015). "A novel tuberculosis antigen identified from human tuberculosis granulomas." Mol Cell Proteomics 14(4): 1093-1103.
6.    Zhang, M., G. Zeng, Q. Yang, J. Zhang, X. Zhu, Q. Chen, P. Suthakaran, Y. Zhang, Q. Deng, H. Liu, B. Zhou and X. Chen (2014). "Anti-tuberculosis treatment enhances the production of IL-22 through reducing the frequencies of regulatory B cell." Tuberculosis (Edinb) 94(3): 238-244.
7.    Liu, L., W. J. Zhang, J. Zheng, H. Fu, Q. Chen, Z. Zhang, X. Chen, B. Zhou, L. Feng, H. Liu and Q. Jin (2014). "Exploration of novel cellular and serological antigen biomarkers in the ORFeome of Mycobacterium tuberculosis." Mol Cell Proteomics 13(3): 897-906.
8.    Hu, S., Y. Zhang, Y. Yu, D. Jin, X. Zhang, S. Gu, H. Jia, X. Chen, Z. Zhang, Q. Jin, Y. Ke and H. Liu (2014). "Growth factor receptor bound protein 2-associated binder 2, a scaffolding adaptor protein, negatively regulates host immunity against tuberculosis." Am J Respir Cell Mol Biol 51(4): 575-585.
9.    Zhang, Y., H. Liu, L. Wang, F. Yang, Y. Hu, X. Ren, G. Li, Y. Yang, S. Sun, Y. Li, X. Chen, X. Li and Q. Jin (2013). "Comparative study of the cytokine/chemokine response in children with differing disease severity in enterovirus 71-induced hand, foot, and mouth disease." PLoS One 8(6): e67430.
10.    Yu, Y., Y. Zhang, S. Hu, D. Jin, X. Chen, Q. Jin and H. Liu (2012). "Different patterns of cytokines and chemokines combined with IFN-gamma production reflect Mycobacterium tuberculosis infection and disease." PLoS One 7(9): e44944.
11.    Qiu, Z., M. Zhang, Y. Zhu, F. Zheng, P. Lu, H. Liu, M. W. Graner, B. Zhou and X. Chen (2012). "Multifunctional CD4 T cell responses in patients with active tuberculosis." Sci Rep 2: 216.
12.    Liu, K., Y. Zhang, S. Hu, Y. Yu, Q. Yang, D. Jin, X. Chen, Q. Jin and H. Liu (2012). "Increased levels of BAFF and APRIL related to human active pulmonary tuberculosis." PLoS One 7(6): e38429.
13.    Zhang, M., Z. Wang, M. W. Graner, L. Yang, M. Liao, Q. Yang, J. Gou, Y. Zhu, C. Wu, H. Liu, B. Zhou and X. Chen (2011). "B cell infiltration is associated with the increased IL-17 and IL-22 expression in the lungs of patients with tuberculosis." Cell Immunol 270(2): 217-223.
14.    Bai, X., K. Chmura, A. R. Ovrutsky, R. P. Bowler, R. I. Scheinman, R. E. Oberley-Deegan, H. Liu, S. Shang, D. Ordway and E. D. Chan (2011). "Mycobacterium tuberculosis increases IP-10 and MIG protein despite inhibition of IP-10 and MIG transcription." Tuberculosis (Edinb) 91(1): 26-35.
15.    Chen, X., M. Zhang, X. Zhu, Q. Deng, H. Liu, N. Larmonier, M. W. Graner and B. Zhou (2009). "Engagement of Toll-like receptor 2 on CD4(+) T cells facilitates local immune responses in patients with tuberculous pleurisy." J Infect Dis 200(3): 399-408.
16.    Niedbala, W., B. Cai, H. Liu, N. Pitman, L. Chang, and F.Y. Liew, Nitric oxide induces CD4+CD25+ Foxp3 regulatory T cells from CD4+CD25 T cells via p53, IL-2, and OX40. Proc Natl Acad Sci U S A, 2007. 104(39): p. 15478-83.
17.    Liu, H. and B.P. Leung, CD4+CD25+ regulatory T cells in health and disease. Clin Exp Pharmacol Physiol, 2006. 33(5-6): p. 519-24.
18.    Liu, H., M. Komai-Koma, D. Xu, and F.Y. Liew, Toll-like receptor 2 signaling modulates the functions of CD4+ CD25+ regulatory T cells. Proc Natl Acad Sci U S A, 2006. 103(18): p. 7048-53.
19.    Liew, F.Y., H. Liu, and D. Xu, A novel negative regulator for IL-1 receptor and Toll-like receptor 4. Immunol Lett, 2005. 96(1): p. 27-31.
20.    Xu, D., H. Liu, and M. Komai-Koma, Direct and indirect role of Toll-like receptors in T cell mediated immunity. Cell Mol Immunol, 2004. 1(4): p. 239-46.
21.    Brint, E.K., D. Xu, H. Liu, A. Dunne, A.N. McKenzie, L.A. O'Neill, and F.Y. Liew, ST2 is an inhibitor of interleukin 1 receptor and Toll-like receptor 4 signaling and maintains endotoxin tolerance. Nat Immunol, 2004. 5(4): p. 373-9
22.    Xu, D., H. Liu, M. Komai-Koma, C. Campbell, C. McSharry, J. Alexander, and F.Y. Liew, CD4+CD25+ regulatory T cells suppress differentiation and functions of Th1 and Th2 cells, Leishmania major infection, and colitis in mice. J Immunol, 2003. 170(1): p. 394-9.
23.    Liu, H., B. Hu, D. Xu, and F.Y. Liew, CD4+CD25+ regulatory T cells cure murine colitis: the role of IL-10, TGF-beta, and CTLA4. J Immunol, 2003. 171(10): p. 5012-7.

培养博士研究生4名，硕士研究生4名，3名硕士研究生在读。